Drug can clear away one fearful memory while leaving another intact.

A single, specific memory has been wiped from the brains of rats, leaving other recollections intact.

The study adds to our understanding of how memories are made and altered in the brain, and could help to relieve sufferers of post-traumatic stress disorder (PTSD) of the fearful memories that disrupt their lives. The results are published in Nature Neuroscience.

The brain secures memories by transferring them from short-term to long-term storage, through a process called reconsolidation. It has been shown before that this process can be interrupted with drugs. But Joseph LeDoux of the Center for Neural Science at New York University and his colleagues wanted to know how specific this interference was: could the transfer of one specific memory be meddled with without affecting others?

“Our concern was: would you do something really massive to their memory network?” says LeDoux.

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